The actors, who married last year (10) after meeting on the set of the hit show, are set to become parents next year (12) and Padalecki confirmed the happy news to fans on Twitter.com.
In a post on the social networking site, he writes, ""OK y'all I'd rather you officially hear it from me... So, yes. Genevieve is pregnant. We'll be welcoming a new member to our family in 2012.""