(Reuters) - Dallas Cowboys rookie running back and top rusher DeMarco Murray is out for the season after suffering a fractured right ankle and high ankle sprain in Sunday's loss to the New York Giants.
His injury is a setback to a Cowboys team that has lost two consecutive games and surrendered sole possession of first place in the NFC East division with three regular season games left.
"It appears like he is gone for the season," Cowboys coach Jason Garrett said.
Murray's lower leg was caught underneath on a tackle by New York defensive end Dave Tollefson on the Cowboys' second drive of the game. He needed the help of two trainers to get off the field.
The third-round pick had rushed for 897 yards on 164 carries. He became the Cowboys' starter after rushing for a team-record 253 yards against the St. Louis Rams in October.
"Minor setback but guarantee I'll be back a better football player!" Murray said on his Twitter account.
(Reporting by Gene Cherry in Salvo North Carolina; Editing by Frank Pingue)